Trifluoromethylacetylenic alcohols as affinity labels: inactivation of estradiol dehydrogenase by a trifluoromethylacetylenic secostradiol

J Med Chem. 1990 Sep;33(9):2319-21. doi: 10.1021/jm00171a002.
No abstract available

Publication types

  • Research Support, Non-U.S. Gov't
  • Research Support, U.S. Gov't, P.H.S.

MeSH terms

  • 17-Hydroxysteroid Dehydrogenases / antagonists & inhibitors*
  • Acetylene / analogs & derivatives*
  • Acetylene / chemical synthesis
  • Acetylene / pharmacology
  • Affinity Labels*
  • Binding Sites
  • Estradiol Dehydrogenases / antagonists & inhibitors*
  • Kinetics

Substances

  • Affinity Labels
  • trifluoromethylacetylene methyl alcohol
  • 17-Hydroxysteroid Dehydrogenases
  • Estradiol Dehydrogenases
  • Acetylene